Phytochelatins and related peptides. Structure, biosynthesis, and function.
نویسنده
چکیده
منابع مشابه
The role of glutathione biosynthesis in heavy metal resistance in the fission yeast Schizosaccharomyces pombe.
Plants and the fission yeast Schizosaccharomyces pombe synthesize small cadmium-binding peptides, called phytochelatins, in response to cadmium. Derived from glutathione (GSH: gamma-Glu-Cys-Gly), they have the general structure (gamma-Glu-Cys)nGly, where n is 2-11. In order to study the biosynthesis of phytochelatins, we used the mutagen N-methyl-N'-nitro-N nitrosoguanidine (MNNG) to select mut...
متن کاملHeavy Metal Detoxification in Plants: Phytochelatin Biosynthesis and Function
Plants have evolved an extensive suite of adaptive responses to heavy metal toxicity. These include the immobilisation, exclusion, chelation and compartmentalisation of metal ions and often involve metal-binding ligands. A number of such ligands have been identified in plants and include organic acids, amino acids, peptides and polypeptides. Polypeptides include the metallothioneins (MTs), smal...
متن کاملPhytochelatins and metallothioneins: roles in heavy metal detoxification and homeostasis.
Among the heavy metal-binding ligands in plant cells the phytochelatins (PCs) and metallothioneins (MTs) are the best characterized. PCs and MTs are different classes of cysteine-rich, heavy metal-binding protein molecules. PCs are enzymatically synthesized peptides, whereas MTs are gene-encoded polypeptides. Recently, genes encoding the enzyme PC synthase have been identified in plants and oth...
متن کاملSecondary Structure Effects on the Acidity of Histidine and Lysine-Based Peptides Model; A Theoretical Study
In this study, the effect of the secondary structure of the protein on the acid strength of three structures of random (R), alpha helix (α) and beta sheet (b) were investigated theoretically. These structures are related to the cationic amino acids of histidine and lysine in the polypeptide chain of eight-glycine residue. Computational methods at the HF, B3LYP, X3LYP and M05-2X levels in t...
متن کاملTolerance and detoxification mechanisms in marine diatom Phaeodactylum tricornutum exposed to cadmium
Tolerance is one of the most important mechanisms for survival. Organisms living in polluted environments with heavy metals develop tolerance to these contaminants; this tolerance has been attributed to the ability to synthesize metal-binding substances or another different mechanism able to mediate metal detoxification. It has been demonstrated that high levels of metals induce the formation o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Plant physiology
دوره 109 4 شماره
صفحات -
تاریخ انتشار 1995